Riboceine Rescues Auranofin-Induced Craniofacial Defects in Zebrafish

• Main Authors: Megan Leask (Author), Catherine Carleton (Author), Bryony Leeke (Author), Trent Newman (Author), Joseph Antoun (Author), Mauro Farella (Author), Julia Horsfield (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Craniofacial abnormalities are a common group of congenital developmental disorders that can require intensive oral surgery as part of their treatment. Neural crest cells (NCCs) contribute to the facial structures; however, they are extremely sensitive to high levels of oxidative stress, which resul...