Glucocorticoid receptors involved in ginsenoside compound K ameliorate adjuvant arthritis by inhibiting the glycolysis of fibroblast-like synoviocytes via the NF-κB/HIF-1α pathway

• Main Authors: Yating Wang (Author), Xiurong Bao (Author), Hao Xian (Author), Fang Wei (Author), Yining Song (Author), Siyu Zhao (Author), Yujie Zhang (Author), Yumeng Wang (Author), Ying Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Ginsenoside metabolite compound K (CK) is an active metabolite produced by ginsenosides in vivo that has an anti-arthritic effect related to the glucocorticoid receptor (GR). However, the potential mechanisms of CK remain unclear.Objective This study explores the role and potential m...