Image-Guided Hydrodynamic Gene Delivery: Current Status and Future Directions

• Main Authors: Kenya Kamimura (Author), Takeshi Yokoo (Author), Hiroyuki Abe (Author), Yuji Kobayashi (Author), Kohei Ogawa (Author), Yoko Shinagawa (Author), Ryosuke Inoue (Author), Shuji Terai (Author)
• Format: Book
• Published: MDPI AG, 2015-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydrodynamics-based delivery has been used as an experimental tool to express transgene in small animals. This in vivo gene transfer method is useful for functional analysis of genetic elements, therapeutic effect of oligonucleotides, and cancer cells to establish the metastatic cancer animal model...