A randomized clinical trial evaluating the efficacy of colistin loading dose in critically ill children

• Main Authors: Shiva Fatehi (Author), Hamid Eshaghi (Author), Meisam Sharifzadeh (Author), Bahador Mirrahimi (Author), Mostafa Qorbani (Author), Parin Tanzifi (Author), Kheirollah Gholami (Author), Toktam Faghihi (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Pharmacokinetic and clinical studies recommend applying loading dose of colistin for the treatment of severe infections in the critically ill adults. Pharmacokinetic studies of colistin in children also highlight the need for a loading dose. However, there are no clinical studies evaluati...