Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhanced α-Synuclein Expression in Mice for Modeling Parkinson's Disease

Parkinson's disease (PD) is characterized by α-synuclein (αSNCA) aggregation in dopaminergic neurons. Gradual accumulation of αSNCA aggregates in substantia nigra (SN) diminishes the normal functioning of soluble αSNCA, leading to a loss of dopamine (DA) neurons. In this study, we developed foc...

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Main Authors: Chung-Yin Lin (Author), Ching-Yun Huang (Author), Chiung-Mei Chen (Author), Hao-Li Liu (Author)
Format: Book
Published: MDPI AG, 2022-02-01T00:00:00Z.
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3rd Floor Main Library

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