Mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of Buruli ulcer.

• Main Authors: John R Wallace (Author), Kirstie M Mangas (Author), Jessica L Porter (Author), Renee Marcsisin (Author), Sacha J Pidot (Author), Brian Howden (Author), Till F Omansen (Author), Weiguang Zeng (Author), Jason K Axford (Author), Paul D R Johnson (Author), Timothy P Stinear (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Addressing the transmission enigma of the neglected disease Buruli ulcer (BU) is a World Health Organization priority. In Australia, we have observed an association between mosquitoes harboring the causative agent, Mycobacterium ulcerans, and BU. Here we tested a contaminated skin model of BU transm...