Optimal experimental design for efficient toxicity testing in microphysiological systems: A bone marrow application

• Main Authors: Jonathan Cairns (Author), Emilyanne Leonard (Author), Kainat Khan (Author), Conor Parks (Author), Gareth Maglennon (Author), Bairu Zhang (Author), Stanley E. Lazic (Author), Lorna Ewart (Author), Rhiannon David (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Microphysiological systems (MPS; organ-on-a-chip) aim to recapitulate the 3D organ microenvironment and improve clinical predictivity relative to previous approaches. Though MPS studies provide great promise to explore treatment options in a multifactorial manner, they are often very c...