Interfering with reconsolidation by rimonabant results in blockade of heroin-associated memory

• Main Authors: Jiang Lin (Author), Yilin Peng (Author), Jinlong Zhang (Author), Junzhe Cheng (Author), Qianqian Chen (Author), Binbin Wang (Author), Yuhang Liu (Author), Shuliang Niu (Author), Jie Yan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-associated pathological memory remains a critical factor contributing to the persistence of substance use disorder. Pharmacological amnestic manipulation to interfere with drug memory reconsolidation has shown promise for the prevention of relapse. In a rat heroin self-administration model, we...