Formulation of stomach-specific floating microparticles of nizatidine and their radiographic evaluation

• Main Authors: Sajjan Singh Seema Rathore (Author), Muniyappa Geetha (Author), Basappa Palur Manjula (Author), Vijaya Gopalachar Joshi (Author), Siddamsetty Ramachandra Setty (Author)
• Format: Book
• Published: Universidade de São Paulo, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Nizatidine is an anti-secretogogue and a gastroprotective drug with a half-life of 1-2 h and is well absorbed in the stomach. This study aimed to optimize the process and develop floating microparticles of nizatidine that are based on low methoxyl pectin. Oil-in-oil dispersion method and Ta...