Advantages and Applications of CAR-Expressing Natural Killer Cells

• Main Authors: Wolfgang eGlienke (Author), Ruth eEsser (Author), Christoph ePriesner (Author), Julia eSuerth (Author), Axel eSchambach (Author), Winfried eWels (Author), Manuel eGrez (Author), Stephan eKloess (Author), Lubomir eArseniev (Author), Ulrike eKoehl (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In contrast to donor T cells, natural killer (NK) cells are known to mediate anti-cancer effects without the risk of inducing graft-versus-host disease (GvHD). In order to improve cytotoxicity against resistant cancer cells, auspicious efforts have been made with chimeric antigen receptor (CAR) expr...