Deciphering the Relationship Between the Trough Concentration of Posaconazole and Its Efficacy and Safety in Chinese Patients With Hematological Disorders

• Main Authors: Meng-Meng Jia (Author), Qi-Wen Zhang (Author), Zi-Fei Qin (Author), Run-Qing Lu (Author), Xue-Ke Tian (Author), Jing Yang (Author), Xiao-Jian Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Posaconazole (PCZ) is effective in preventing and salvage treatment invasive fungal infections in patients with hematologic disorders. However, PCZ displays highly variable individual pharmacokinetics affecting its efficacy and safety. To investigate the correlation between PCZ concentration and eff...