High Phosphate-Induced Calcification of Vascular Smooth Muscle Cells is Associated with the TLR4/NF-κb Signaling Pathway

• Main Authors: Daohai Zhang (Author), Xianjin Bi (Author), Yong Liu (Author), Yinghui Huang (Author), Jiachuan Xiong (Author), Xinli Xu (Author), Tangli Xiao (Author), Yanlin Yu (Author), Wei Jiang (Author), Yunjian Huang (Author), Jingbo Zhang (Author), Bo Zhang (Author), Jinghong Zhao (Author)
• Format: Book
• Published: Karger Publishers, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Hyperphosphatemia is one of the most notable features of chronic kidney disease (CKD). Numerous epidemiological and clinical studies have found that high serum phosphate concentrations are associated with calcification in the coronary arteries. However, the mechanisms underlying the...