Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression

• Main Authors: Ying Meng (Author), Mengli Jin (Author), Dai Yuan (Author), Yicheng Zhao (Author), Xiangri Kong (Author), Xuerui Guo (Author), Xingye Wang (Author), Juan Hou (Author), Bingmei Wang (Author), Wu Song (Author), Yong Tang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypopharyngeal squamous cell carcinoma (HSCC) is one of the high mortality cancers with a poor prognosis, which is driving the development of new chemotherapeutic agents. We identified the anticancer effects of a natural compound, solamargine (SM), on FaDU cells and explored its mechanism in terms o...