Knockdown of Pnpla6 protein results in motor neuron defects in zebrafish

• Main Authors: Yang Song (Author), Molin Wang (Author), Fei Mao (Author), Ming Shao (Author), Baochang Zhao (Author), Zhen Song (Author), Changshun Shao (Author), Yaoqin Gong (Author)
• Format: Book
• Published: The Company of Biologists, 2013-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Mutations in patatin-like phospholipase domain containing 6 (PNPLA6), also known as neuropathy target esterase (NTE) or SPG39, cause hereditary spastic paraplegia (HSP). Although studies on animal models, including mice and Drosophila, have extended our understanding of PNPLA6, its roles in...