Decreased glutamate transport in acivicin resistant Leishmania tarentolae.

• Үндсэн зохиолчид: Gaétan Roy (Зохиогч), Arijit Bhattacharya (Зохиогч), Philippe Leprohon (Зохиогч), Marc Ouellette (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Public Library of Science (PLoS), 2021-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Studies of drug resistance in the protozoan parasites of the genus Leishmania have been helpful in revealing biochemical pathways as potential drug targets. The chlorinated glutamine analogue acivicin has shown good activity against Leishmania cells and was shown to target several enzymes containing...