Single-cell transcriptomic analysis uncovers the origin and intratumoral heterogeneity of parotid pleomorphic adenoma

• Main Authors: Xiuyun Xu (Author), Jiaxiang Xie (Author), Rongsong Ling (Author), Shengqi Ouyang (Author), Gan Xiong (Author), Yanwen Lu (Author), Bokai Yun (Author), Ming Zhang (Author), Wenjin Wang (Author), Xiqiang Liu (Author), Demeng Chen (Author), Cheng Wang (Author)
• Format: Book
• Published: Nature Publishing Group, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pleomorphic adenoma (PA) is the most common benign tumour in the salivary gland and has high morphological complexity. However, the origin and intratumoral heterogeneity of PA are largely unknown. Here, we constructed a comprehensive atlas of PA at single-cell resolution and showed that PA...