Cepharanthine induces ROS stress in glioma and neuronal cells via modulation of VDAC permeability
Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid. Molecular dynamics studies show that CEP interacts with Voltage-dependent anion channel (VDAC), inducing the voltage-independent channel narrowing. In the new conformation, transport between mitochondria and cytoplasm is altered, which leads t...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2020-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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