Mesenchymal Stem Cells Enhance Therapeutic Effect and Prevent Adverse Gastrointestinal Reaction of Methotrexate Treatment in Collagen-Induced Arthritis

• Autores principales: Qiming Zhai (Autor), Jiayi Dong (Autor), Xuesi Zhang (Autor), Xiaoning He (Autor), Dongdong Fei (Autor), Yan Jin (Autor), Bei Li (Autor), Fang Jin (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2021-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by articular destruction and functional loss. Methotrexate (MTX) is effective in RA treatment. However, MTX induces several adverse events and 20%-30% of patients do not respond to MTX. Thus, it is urgent to enhance the therape...