Genome Mining and Metabolic Profiling Reveal Cytotoxic Cyclodipeptides in <i>Streptomyces hygrospinosus</i> var. Beijingensis

• Main Authors: Dashan Zhang (Author), Junbo Wang (Author), Yongjian Qiao (Author), Baixin Lin (Author), Zixin Deng (Author), Lingxin Kong (Author), Delin You (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Two new cyclodipeptide (CDP) derivatives (<b>1-2</b>) and another seven known cyclodipeptides (<b>3-9</b>) were isolated from <i>Streptomyces</i> 26D9-414 by the genome mining approach combined with genetic dereplication and the "one strain many compounds&quo...