Identifying problematic drugs based on the characteristics of their targets

• Main Authors: Tiago Jose eDa Silva Lopes (Author), Jason Edward Shoemaker (Author), Yukiko eMatsuoka (Author), Hiroaki eKitano (Author), Yoshihiro eKawaoka (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Identifying promising compounds during the early stages of drug development is a major challenge for both academia and the pharmaceutical industry. The difficulties are even more pronounced when we consider multi-target pharmacology, where the compounds often target more than one protein, or multipl...