CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms

• Main Authors: Deepak A. Deshpande (Author), Alonso G. P. Guedes (Author), Richard Graeff (Author), Soner Dogan (Author), Subbaya Subramanian (Author), Timothy F. Walseth (Author), Mathur S. Kannan (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Asthma is an inflammatory disease in which proinflammatory cytokines have a role in inducing abnormalities of airway smooth muscle function and in the development of airway hyperresponsiveness. Inflammatory cytokines alter calcium (Ca2+) signaling and contractility of airway smooth muscle, which res...