Population pharmacokinetics of apixaban in a real‐life hospitalized population from the OptimAT study

• Main Authors: Frédéric Gaspar (Author), Jean Terrier (Author), Samantha Favre (Author), Pauline Gosselin (Author), Pierre Fontana (Author), Youssef Daali (Author), Camille Lenoir (Author), Caroline Flora Samer (Author), Victoria Rollason (Author), Jean‐Luc Reny (Author), Chantal Csajka (Author), Monia Guidi (Author)
• Format: Book
• Published: Wiley, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This study aimed to characterize apixaban pharmacokinetics (PKs) and its variability in a real‐world clinical setting of hospitalized patients using a population PK (PopPK) approach. Model‐based simulations helped to identify factors that affect apixaban exposure and their clinical signific...