Development of Chitosan/Cyclodextrin Nanospheres for Levofloxacin Ocular Delivery

• Main Authors: Federica De Gaetano (Author), Andreana Marino (Author), Alessia Marchetta (Author), Corrado Bongiorno (Author), Roberto Zagami (Author), Maria C. Cristiano (Author), Donatella Paolino (Author), Venerando Pistarà (Author), Cinzia A. Ventura (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Levofloxacin (LVF) is an antibacterial drug approved for the treatment of ocular infections. However, due to the low ocular bioavailability, high doses are needed, causing bacterial resistance. Polymeric nanospheres (NPs) loading antibiotic drugs represent the most promising approach to eradicate oc...