Loxosceles gaucho venom-induced acute kidney injury--in vivo and in vitro studies.

• Main Authors: Rui V Lucato (Author), Regina C R M Abdulkader (Author), Katia C Barbaro (Author), Glória E Mendes (Author), Isac Castro (Author), Maria A S F Baptista (Author), Patrícia M Cury (Author), Denise M C Malheiros (Author), Nestor Schor (Author), Luis Yu (Author), Emmanuel A Burdmann (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Accidents caused by Loxosceles spider may cause severe systemic reactions, including acute kidney injury (AKI). There are few experimental studies assessing Loxosceles venom effects on kidney function in vivo. METHODOLOGY/PRINCIPAL FINDINGS: In order to test Loxosceles gaucho venom (LV)...