Enzymatic approaches for profiling cytosine methylation and hydroxymethylation

Background: In mammals, modifications to cytosine bases, particularly in cytosine-guanine (CpG) dinucleotide contexts, play a major role in shaping the epigenome. The canonical epigenetic mark is 5-methylcytosine (5mC), but oxidized versions of 5mC, including 5-hydroxymethylcytosine (5hmC), are now...

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Main Authors: Tong Wang (Author), Christian E. Loo (Author), Rahul M. Kohli (Author)
Format: Book
Published: Elsevier, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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