Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine

The ether lipid edelfosine induces apoptosis selectively in tumor cells and is the prototypic molecule of a family of synthetic antitumor compounds collectively known as alkylphospholipid analogs. Cumulative evidence shows that edelfosine interacts with cholesterol-rich lipid rafts, endoplasmic reti...

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Main Authors: Faustino Mollinedo (Author), Consuelo Gajate (Author)
Format: Book
Published: MDPI AG, 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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