Cancer-targeted design of bioresponsive prodrug with enhanced cellular uptake to achieve precise cancer therapy

• Main Authors: Yuanwei Liang (Author), Wei Huang (Author), Delong Zeng (Author), Xiaoting Huang (Author), Leung Chan (Author), Chaoming Mei (Author), Pengju Feng (Author), Choon-Hong Tan (Author), Tianfeng Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemical drug design based on the biochemical characteristics of cancer cells has become an important strategy for discovery of novel anticancer drugs to enhance the cancer targeting effects and biocompatibility, and decrease toxic side effects. Camptothecin (CPT) demonstrated strong anticancer acti...