Clinical significance of measuring ADAMTS-13, its inhibitor and von Willebrand factor in obstetric and gynecological practice

• Main Authors: K. N. Grigoreva (Author), V. O. Bitsadze (Author), J. Kh. Khizroeva (Author), M. V. Tretyakova (Author), D. A. Ponomarev (Author), K. Yu. Tsvetnova (Author), D. A. Doronicheva (Author), A. R. Mamaeva (Author), K. V. Mekhedova (Author), G. Rizzo (Author), J.-C. Gris (Author), I. Elalamy (Author), A. D. Makatsariya (Author)
• Format: Book
• Published: IRBIS LLC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ADAMTS-13 is a crucial metalloproteinase involved in liberating fragments of von Willebrand factor (vWF) into the plasma as well as regulating its activity by cleaving "ultra-large" multimers into smaller and less active counterparts. Many pathological conditions, including those emerged d...