Possible Involvement of Both Endoplasmic Reticulumand Mitochondria-Dependent Pathways in Thapsigargin-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells

• Asıl Yazarlar: Yoshihisa Kitamura (Yazar), Atsushi Miyamura (Yazar), Kazuyuki Takata (Yazar), Masatoshi Inden (Yazar), Daiju Tsuchiya (Yazar), Kumi Nakamura (Yazar), Takashi Taniguchi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2003-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Recently, it has been shown that endoplasmic reticulum (ER) stress causes apoptosis. However, the mechanism of the ER stress-dependent pathway is not fully understood. In human neuroblastoma SH-SY5Y cells, we detected a caspase-12-like protein that has a molecular mass (approximately 60 kDa) similar...