Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy

• Main Authors: Caiqiong Liu (Author), Xiaoyan Li (Author), Lanjun Shuai (Author), Xiqiang Dang (Author), Fangrong Peng (Author), Mingyi Zhao (Author), Shiqiu Xiong (Author), Ying Liu (Author), Qingnan He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The factor associated with IgA nephropathy (IgAN) is an abnormality of IgA known as galactose-deficient IgA1 (Gd-IgA1). The purpose of this study was to determine the molecular role played by miRNAs in the formation of Gd-IgA1 in IgAN and investigate the regulatory role of Astragaloside IV...