Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels

• Main Authors: Cohen William (Author), Germain Marine (Author), Dimitromanolakis Apostolos (Author), Oudot-Mellakh Tiphaine (Author), Antoni Guillemette (Author), Wells Philip (Author), Lathrop Mark (Author), Gagnon France (Author), Morange Pierre-Emmanuel (Author), Tregouet David-Alexandre (Author)
• Format: Book
• Published: BMC, 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Elevated levels of factor VIII (FVIII) and von Willebrand Factor (vWF) are well-established risk factors for cardiovascular diseases, in particular venous thrombosis. Although high, the heritability of these traits is poorly explaine...