Optimized Ribociclib nanostructured lipid carrier for the amelioration of skin cancer: Inferences from ex-vivo skin permeation and dermatokinetic studies

• Main Authors: Mohammed F. Aldawsari (Author), Mohammad Azhar Kamal (Author), Mohamed F. Balaha (Author), Talha Jawaid (Author), Mohammed Jafar (Author), Sana Hashmi (Author), Majid Ahmad Ganaie (Author), Aftab Alam (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current research focuses on explicitly developing and evaluating nanostructured lipidic carriers (NLCs) for the chemotherapeutic drug Ribociclib (RCB) via the topical route to surmount the inherent bioavailability shortcomings. The absolute oral bioavailability has not been determined, but using a p...