Analgesic Activity, Chemical Profiling and Computational Study on Chrysopogon aciculatus

• Main Authors: S. M. Neamul Kabir Zihad (Author), Niloy Bhowmick (Author), Shaikh Jamal Uddin (Author), Nazifa Sifat (Author), Md. Shamim Rahman (Author), Razina Rouf (Author), Muhammad Torequl Islam (Author), Shrabanti Dev (Author), Hazrina Hazni (Author), Shahin Aziz (Author), Eunüs S. Ali (Author), Asish K. Das (Author), Jamil A. Shilpi (Author), Lutfun Nahar (Author), Satyajit D. Sarker (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Present study was undertaken to evaluate the analgesic activity of the ethanol extract of Chrysopogon aciculatus. In addition to bioassays in mice, chemical profiling was done by LC-MS and GC-MS to identify phytochemicals, which were further docked on the catalytic site of COX-2 enzymes with a view...