GIMAP7 induces oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome by inhibiting sonic hedgehog signalling pathway

Highlights 1. GIMAP7 is upregulated in ovary granulosa cells of PCOS rat; 2. GIMAP7 shRNA relieves the symptoms of PCOS rats; 3. GIMAP7 shRNA inhibits the apoptosis and oxidative stress of KGN cells; 4. GIMAP7 inhibits sonic hedgehog signalling pathway in KGN cells.

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Bibliographic Details
Main Authors: Anran Xu (Author), Yuanyuan Fan (Author), Song Liu (Author), Lianbing Sheng (Author), Yanyan Sun (Author), Huijun Yang (Author)
Format: Book
Published: BMC, 2022-12-01T00:00:00Z.
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3rd Floor Main Library

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