Effects of Rikkunshi-To, a Japanese kampo medicine, on donepezil-induced gastrointestinal side effects in mice

• 主要な著者: Kouichi Yamamoto (著者), Yuhki Sato (著者), Keisuke Hagihara (著者), Kyosuke Kirikihira (著者), Akito Jotaki (著者), Ayana Michihara (著者), Yumi Miyake (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2022-10-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Donepezil, an acetylcholinesterase inhibitor, is associated with gastrointestinal symptoms, such as nausea, vomiting, and anorexia, which may affect adherence to continuous therapy. Since Rikkunshi-To, a Japanese herbal medicine, activates the ghrelin signaling pathway and promotes gastrointestinal...