Vitamin E Phosphate Nucleoside Prodrugs: A Platform for Intracellular Delivery of Monophosphorylated Nucleosides

Vitamin E phosphate (VEP) nucleoside prodrugs are designed to bypass two mechanisms of tumor resistance to therapeutic nucleosides: nucleoside transport and kinase downregulation. Certain isoforms of vitamin E (VE) have shown activity against solid and hematologic tumors and result in chemosensitiza...

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Bibliographic Details
Main Authors: Richard Daifuku (Author), Michael Koratich (Author), Murray Stackhouse (Author)
Format: Book
Published: MDPI AG, 2018-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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