In silico Analyses of Immune System Protein Interactome Network, Single-Cell RNA Sequencing of Human Tissues, and Artificial Neural Networks Reveal Potential Therapeutic Targets for Drug Repurposing Against COVID-19

• Main Authors: Andrés López-Cortés (Author), Patricia Guevara-Ramírez (Author), Nikolaos C. Kyriakidis (Author), Carlos Barba-Ostria (Author), Ángela León Cáceres (Author), Santiago Guerrero (Author), Esteban Ortiz-Prado (Author), Cristian R. Munteanu (Author), Eduardo Tejera (Author), Doménica Cevallos-Robalino (Author), Ana María Gómez-Jaramillo (Author), Katherine Simbaña-Rivera (Author), Adriana Granizo-Martínez (Author), Gabriela Pérez-M (Author), Silvana Moreno (Author), Jennyfer M. García-Cárdenas (Author), Ana Karina Zambrano (Author), Yunierkis Pérez-Castillo (Author), Alejandro Cabrera-Andrade (Author), Lourdes Puig San Andrés (Author), Carolina Proaño-Castro (Author), Jhommara Bautista (Author), Andreina Quevedo (Author), Nelson Varela (Author), Luis Abel Quiñones (Author), César Paz- (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: There is pressing urgency to identify therapeutic targets and drugs that allow treating COVID-19 patients effectively.Methods: We performed in silico analyses of immune system protein interactome network, single-cell RNA sequencing of human tissues, and artificial neural networks to reve...