TRIP6 promotes inflammatory damage via the activation of TRAF6 signaling in a murine model of DSS-induced colitis

• Main Authors: Yun Yang (Author), Xiu-Ming Li (Author), Jing-Ru Wang (Author), Yan Li (Author), Wen-Long Ye (Author), Yi Wang (Author), Yu-Xuan Liu (Author), Zhi-Yong Deng (Author), Wen-Juan Gan (Author), Hua Wu (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background TRIP6 is a zyxin family member that serves as an adaptor protein to regulate diverse biological processes. In prior reports, TRIP6 was shown to play a role in regulating inflammation. However, its in vivo roles and mechanistic importance in colitis remain largely elusive. Herein,...