Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability

• Автори: Gang Wang (Автор), Lichun Zhao (Автор), Qikun jiang (Автор), Yixin Sun (Автор), Dongyang Zhao (Автор), Mengchi Sun (Автор), Zhonggui He (Автор), Jin sun (Автор), Yang Wang (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2020-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Various drug transporters are widely expressed throughout the intestine and play important roles in absorbing nutrients and drugs, thus providing high quality targets for the design of prodrugs or nanoparticles to facilitate oral drug delivery. In particular, intestinal carnitine/organic cation tran...