Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability

• Main Authors: Gang Wang (Author), Lichun Zhao (Author), Qikun jiang (Author), Yixin Sun (Author), Dongyang Zhao (Author), Mengchi Sun (Author), Zhonggui He (Author), Jin sun (Author), Yang Wang (Author)
• Format: Book
• Published: Elsevier, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Various drug transporters are widely expressed throughout the intestine and play important roles in absorbing nutrients and drugs, thus providing high quality targets for the design of prodrugs or nanoparticles to facilitate oral drug delivery. In particular, intestinal carnitine/organic cation tran...