Interactions Between Emodin and Efflux Transporters on Rat Enterocyte by a Validated Ussing Chamber Technique

• Main Authors: Juan Huang (Author), Lan Guo (Author), Ruixiang Tan (Author), Meijin Wei (Author), Jing Zhang (Author), Ya Zhao (Author), Lu Gong (Author), Zhihai Huang (Author), Xiaohui Qiu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Emodin, a major active anthraquinone, frequently interacts with other drugs. As changes of efflux transporters on intestine are one of the essential reasons why the drugs interact with each other, a validated Ussing chamber technique was established to detect the interactions between emodin and effl...