Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel

• Main Authors: Dawei Ding (Author), Bingjun Sun (Author), Weiping Cui (Author), Qin Chen (Author), Xuanbo Zhang (Author), Haotian Zhang (Author), Zhonggui He (Author), Jin Sun (Author), Cong Luo (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However, large polarity molecules with insufficient lipid solubility, such as paclitaxel (PTX), would suffer from inferior formulation...