Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?

• Main Authors: Philippa C. Matthews (Author), Cori Campbell (Author), Oana Săndulescu (Author), Mojca Matičič (Author), Simona Maria Ruta (Author), Antonio Rivero-Juárez (Author), Berend Joost van Welzen (Author), Boun Kim Tan (Author), Federico Garcia (Author), George Sebastian Gherlan (Author), Güle Çınar (Author), İmran Hasanoğlu (Author), Ivana Gmizić (Author), Laura Ambra Nicolini (Author), Lurdes Santos (Author), Narina Sargsyants (Author), Petar Velikov (Author), Selma Habibović (Author), Slim Fourati (Author), Snježana Židovec-Lepej (Author), Vanessa Herder (Author), Susanne Dudman (Author), Victor Daniel Miron (Author), William Irving (Author), Gülşen Özkaya Şahin (Author), and ESCMID Study Group for Viral Hepatitis (ESGVH) (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged <6 years. Sp...