Regulation of macrophage polarization by targeted metabolic reprogramming for the treatment of lupus nephritis

• Main Authors: Limei Zhao (Author), Shuqin Tang (Author), Fahui Chen (Author), Xiya Ren (Author), Xiutao Han (Author), Xiaoshuang Zhou (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Lupus nephritis (LN) is a severe and common manifestation of systemic lupus erythematosus (SLE) that is frequently identified with a poor prognosis. Macrophages play an important role in its pathogenesis. Different macrophage subtypes have different effects on lupus-affected kidneys. Based...