Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

• Hoofdauteurs: Chung Jae (Auteur), Jeong Mikyoung (Auteur), Montgomery John S (Auteur), Balch Curt (Auteur), Li Meng (Auteur), Yan Pearlly (Auteur), Huang Tim HM (Auteur), Kim Sun (Auteur), Nephew Kenneth P (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2009-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Cisplatin and carboplatin are the primary first-line therapies for the treatment of ovarian cancer. However, resistance to these platinum-based drugs occurs in the large majority of initially responsive tumors, resulting in fully che...