Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

• मुख्य लेखकों: Chung Jae (लेखक), Jeong Mikyoung (लेखक), Montgomery John S (लेखक), Balch Curt (लेखक), Li Meng (लेखक), Yan Pearlly (लेखक), Huang Tim HM (लेखक), Kim Sun (लेखक), Nephew Kenneth P (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2009-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Cisplatin and carboplatin are the primary first-line therapies for the treatment of ovarian cancer. However, resistance to these platinum-based drugs occurs in the large majority of initially responsive tumors, resulting in fully che...