Crocin attenuates osteoclastogenesis and enhances bone health by skewing the immunoporotic "Treg-Th17" cell axis in post-menopausal osteoporotic mice model

• Main Authors: Zaffar Azam (Author), Leena Sapra (Author), Asha Bhardwaj (Author), Sumedha Yadav (Author), Pradyumna K. Mishra (Author), Prashant Shukla (Author), Versha Sharma (Author), Rupesh K. Srivastava (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Crocin is a well-known carotenoid with established anti-inflammatory, anti-arthritic, anti-tumor, and antioxidant properties. Previous studies have also identified crocin as a potential drug candidate for osteoporosis treatment; however, the mechanisms underlying its direct influence on...