Towards Personalized Allele-Specific Antisense Oligonucleotide Therapies for Toxic Gain-of-Function Neurodegenerative Diseases
Antisense oligonucleotides (ASOs) are single-stranded nucleic acid strings that can be used to selectively modify protein synthesis by binding complementary (pre-)mRNA sequences. By specific arrangements of DNA and RNA into a chain of nucleic acids and additional modifications of the backbone, sugar...
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| Main Authors: | , , |
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| Format: | Book |
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MDPI AG,
2022-08-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |