Antibody-mediated delivery of LIGHT to the tumor boosts natural killer cells and delays tumor progression
LIGHT is a member of the tumor necrosis factor superfamily, which has been claimed to mediate anti-tumor activity on the basis of cancer cures observed in immunocompetent mice bearing transgenic LIGHT-expressing tumors. The preclinical development of a LIGHT-based therapeutic has been hindered by th...
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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