Effect of adoptive transfer or depletion of regulatory T cells on triptolide-induced liver injury

• Main Authors: Xinzhi eWang (Author), Lixin eSun (Author), Luyong eZhang (Author), Zhenzhou eJiang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ObjectiveThe aim of this study is to clarify the role of regulatory T cell (Treg) in triptolide (TP)-induced hepatotoxicity. MethodsFemale C57BL/6 mice received either adoptive transfer of Tregs or depletion of Tregs, then underwent TP administration and were sacrificed 24 hours after TP administrat...