Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport

Isobutyrylcarnitine as a Biomarker of OCT1 Activity and Interspecies Differences in its Membrane Transport

Genome-wide association studies have identified an association between isobutyrylcarnitine (IBC) and organic cation transporter 1 (OCT1) genotypes. Higher IBC blood concentrations in humans with active OCT1 genotypes and experimental studies with mouse OCT1 suggested an OCT1-mediated efflux of IBC....

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Main Authors: Ole Jensen (Author), Johannes Matthaei (Author), Henry G. Klemp (Author), Marleen J. Meyer (Author), Jürgen Brockmöller (Author), Mladen V. Tzvetkov (Author)
Format: Book
Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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