Navigating therapeutic challenges in VEXAS syndrome: exploring IL-6 and JAK inhibitors at the forefront

• Main Authors: Xiao Xiao Li (Author), Wen Hui Huang (Author), Xiao Bin Yang (Author), Qi Lin Yang (Author), Yu Zheng (Author), Yong Bao Huo (Author), Ting Ting Xie (Author), Cheng Hui Huang (Author), Shui Lian Yu (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract VEXAS syndrome, an uncommon yet severe autoimmune disorder stemming from a mutation in the UBA1 gene, is the focus of this paper. The overview encompasses its discovery, epidemiological traits, genetic underpinnings, and clinical presentations. Delving into whether distinct genotypes yield...